African swine fever virus (ASFV): Biology, genomics and genotypes circulating in sub-Saharan Africa

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cg.authorship.typesCGIAR and developing country instituteen
cg.authorship.typesCGIAR and advanced research instituteen
cg.contributor.affiliationInternational Livestock Research Instituteen
cg.contributor.affiliationNelson Mandela African Institution of Science and Technologyen
cg.contributor.affiliationSokoine University of Agricultureen
cg.contributor.affiliationUniversity of Glasgowen
cg.contributor.affiliationMzumbe Universityen
cg.contributor.donorAfrica Biosciences Challenge Funden
cg.coverage.regionAfrica
cg.coverage.regionSub-Saharan Africa
cg.creator.identifierEmma Njau: 0000-0002-0489-5863
cg.creator.identifierEunice Machuka: 0000-0002-1142-3442
cg.creator.identifierRoger Pelle: 0000-0003-1053-085X
cg.creator.identifierGabriel Shirima: 0000-0001-7768-711X
cg.creator.identifierAbworo: 0000-0003-0689-823X
cg.howPublishedFormally Publisheden
cg.identifier.doihttps://doi.org/10.3390/v13112285en
cg.isijournalISI Journalen
cg.issn1999-4915en
cg.issue11en
cg.journalVirusesen
cg.reviewStatusPeer Reviewen
cg.subject.ilriASFen
cg.subject.ilriPIGSen
cg.subject.impactAreaNutrition, health and food security
cg.subject.sdgSDG 2 - Zero hungeren
cg.volume13en
dc.contributor.authorNjau, Emma P.en
dc.contributor.authorMachuka, Eunice M.en
dc.contributor.authorCleaveland, S.en
dc.contributor.authorShirima, G.M.en
dc.contributor.authorKusiluka, L.J.en
dc.contributor.authorOkoth, Edward A.en
dc.contributor.authorPelle, Rogeren
dc.date.accessioned2021-11-30T16:14:55Zen
dc.date.available2021-11-30T16:14:55Zen
dc.identifier.urihttps://hdl.handle.net/10568/116402
dc.titleAfrican swine fever virus (ASFV): Biology, genomics and genotypes circulating in sub-Saharan Africaen
dcterms.abstractAfrican swine fever (ASF) is a highly infectious and fatal haemorrhagic disease of pigs that is caused by a complex DNA virus of the genus Asfivirus and Asfarviridae African suids family. The disease is among the most devastating pig diseases worldwide including Africa. Although the disease was first reported in the 19th century, it has continued to spread in Africa and other parts of the world. Globally, the rising demand for pork and concomitant increase in transboundary movements of pigs and pork products is likely to increase the risk of transmission and spread of ASF and pose a major challenge to the pig industry. Different genotypes of the ASF virus (ASFV) with varying virulence have been associated with different outbreaks in several countries in sub-Saharan Africa (SSA) and worldwide, and understanding genotype circulation will be important for ASF prevention and control strategies. ASFV genotypes unique to Africa have also been reported in SSA. This review briefly recounts the biology, genomics and genotyping of ASFV and provides an account of the different genotypes circulating in SSA. The review also highlights prevention, control and progress on vaccine development and identifies gaps in knowledge of ASFV genotype circulation in SSA that need to be addressed.en
dcterms.accessRightsOpen Access
dcterms.audienceAcademicsen
dcterms.audienceScientistsen
dcterms.available2021-11-15
dcterms.bibliographicCitationNjau, E.P., Machuka, E.M., Cleaveland, S., Shirima, G.M., Kusiluka, L.J., Okoth, E.A. and Pelle, R. 2021. African swine fever virus (ASFV): Biology, genomics and genotypes circulating in sub-Saharan Africa. Viruses 13(11): 2285.en
dcterms.extent2285en
dcterms.issued2021-11-15
dcterms.languageen
dcterms.licenseCC-BY-4.0
dcterms.publisherMDPIen
dcterms.subjectafrican swine fever virusen
dcterms.subjectswineen
dcterms.subjectgenomicsen
dcterms.subjectvirologyen
dcterms.subjectinfectious diseasesen
dcterms.typeJournal Article

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