Knockout of cadmium sensitive gene 1 confers enhanced cadmium tolerance in rice (Oryza sativa L.) by regulating the subcellular distribution of cadmium

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cg.authorship.typesCGIAR and developing country instituteen
cg.contributor.affiliationTianjin Normal Universityen
cg.contributor.affiliationChinese Academy of Agricultural Sciencesen
cg.contributor.affiliationShenzhen Agricultural Science and Technology Promotion Centeren
cg.contributor.affiliationHunan Hybrid Rice Research Centeren
cg.contributor.affiliationInternational Rice Research Instituteen
cg.contributor.donorNational Natural Science Foundation of Chinaen
cg.contributor.donorInternational Rice Research Instituteen
cg.contributor.donorTianjin Rice Industrial Technology System of Chinaen
cg.creator.identifierGuoyou Ye: 0000-0002-9943-4815en
cg.howPublishedFormally Publisheden
cg.identifier.doihttps://doi.org/10.1016/j.ijbiomac.2025.141604en
cg.identifier.urlhttps://www.sciencedirect.com/science/article/abs/pii/S0141813025021555?via%3Dihuben
cg.isijournalISI Journalen
cg.issn0141-8130en
cg.issue4en
cg.journalInternational Journal of Biological Macromoleculesen
cg.reviewStatusPeer Reviewen
cg.volumeVolume 306en
dc.contributor.authorLiang, Shanshanen
dc.contributor.authorLan, Zhipengen
dc.contributor.authorWang, Jiahanen
dc.contributor.authorZou, Wenlien
dc.contributor.authorHu, Youchuanen
dc.contributor.authorRan, Hongyuen
dc.contributor.authorQin, Maoen
dc.contributor.authorXiao, Guien
dc.contributor.authorZhang, Sijuen
dc.contributor.authorMa, Xuanen
dc.contributor.authorYe, Guoyouen
dc.contributor.authorLuan, Weijiangen
dc.date.accessioned2025-04-30T08:48:41Zen
dc.date.available2025-04-30T08:48:41Zen
dc.identifier.urihttps://hdl.handle.net/10568/174395
dc.titleKnockout of cadmium sensitive gene 1 confers enhanced cadmium tolerance in rice (Oryza sativa L.) by regulating the subcellular distribution of cadmiumen
dcterms.abstractCadmium (Cd) is a heavy metal which is toxic to both plants and animal. The high content of Cd in the rice grain severely threatens human's health. Here, we identified a Cd sensitive gene, named Cadmium Sensitive Gene 1 (OsCSG1), playing an important role in improving Cd tolerance in rice at seedling stage. The expression of OsCSG1 was induced by CdCl2 and exhibited higher mRNA levels in leaf blade, leaf sheath and stele of roots. Knockout of OsCSG1 improved the Cd tolerance of rice seedlings, suggesting that OsCSG1 negatively regulated Cd tolerance in rice. The Cd concentration in roots of seedling of oscsg1 mutants increased significantly under Cd stress, but not in the shoot and grains compared with wild type (WT). Subcellular distribution of Cd in root cells suggested that Cd proportions in soluble fractions of cells in oscsg1 mutant increased significantly. And CAT activity in oscsg1 mutants increased significantly. Taken together, knocking out OsCSG1 could improve Cd tolerance in rice by regulating subcellular distribution of cadmium and increased CAT activity.en
dcterms.accessRightsLimited Access
dcterms.audienceAcademicsen
dcterms.audienceCGIARen
dcterms.audienceDevelopment Practitionersen
dcterms.audienceScientistsen
dcterms.available2025-03-07en
dcterms.bibliographicCitationLiang, Shanshan, Zhipeng Lan, Jiahan Wang, Wenli Zou, Youchuan Hu, Hongyu Ran, Mao Qin et al. "Knockout of cadmium sensitive gene 1 confers enhanced cadmium tolerance in rice (Oryza sativa L.) by regulating the subcellular distribution of cadmium." International Journal of Biological Macromolecules 306 (2025): 141604.en
dcterms.extent141604en
dcterms.issued2025-02-28en
dcterms.languageen
dcterms.licenseCopyrighted; all rights reserved
dcterms.publisherElsevier BVen
dcterms.subjectcadmiumen
dcterms.subjectheavy metalsen
dcterms.subjecttoxicityen
dcterms.subjectgene expressionen
dcterms.subjectmutantsen
dcterms.subjectroot systemen
dcterms.subjectshootsen
dcterms.subjectgrainsen
dcterms.subjectabiotic stressen
dcterms.subjectriceen
dcterms.typeJournal Article

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