Analyses of Twelve New Whole Genome Sequences of Cassava Brown Streak Viruses and Ugandan Cassava Brown Streak Viruses from East Africa: Diversity, Supercomputing and Evidence for Further Speciation

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cg.contributor.affiliationDepartment of Agriculture and Food, Western Australiaen_US
cg.contributor.affiliationInternational Livestock Research Instituteen_US
cg.contributor.affiliationMikocheni Agricultural Research Instituteen_US
cg.contributor.affiliationUniversity of Western Australiaen_US
cg.contributor.donorBill & Melinda Gates Foundationen_US
cg.creator.identifierAppolinaire Djikeng: 0000-0001-9271-3419en_US
cg.identifier.doihttps://doi.org/10.1371/journal.pone.0139321en_US
cg.issn1932-6203en_US
cg.issue10en_US
cg.journalPLOS ONEen_US
cg.volume10en_US
dc.contributor.authorNdunguru, Josephen_US
dc.contributor.authorSseruwagi, Peteren_US
dc.contributor.authorTairo, Freden_US
dc.contributor.authorStomeo, Francescaen_US
dc.contributor.authorMaina, Solomonen_US
dc.contributor.authorDjikeng, Appolinaireen_US
dc.contributor.authorKehoe, Monicaen_US
dc.contributor.authorBoykin, Laura M.en_US
dc.date.accessioned2023-03-10T14:36:33Zen_US
dc.date.available2023-03-10T14:36:33Zen_US
dc.identifier.urihttps://hdl.handle.net/10568/129485en_US
dc.titleAnalyses of Twelve New Whole Genome Sequences of Cassava Brown Streak Viruses and Ugandan Cassava Brown Streak Viruses from East Africa: Diversity, Supercomputing and Evidence for Further Speciationen_US
dcterms.abstractCassava brown streak disease is caused by two devastating viruses, Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV) which are frequently found infecting cassava, one of sub-Saharan Africa’s most important staple food crops. Each year these viruses cause losses of up to $100 million USD and can leave entire families without their primary food source, for an entire year. Twelve new whole genomes, including seven of CBSV and five of UCBSV were uncovered in this research, doubling the genomic sequences available in the public domain for these viruses. These new sequences disprove the assumption that the viruses are limited by agro-ecological zones, show that current diagnostic primers are insufficient to provide confident diagnosis of these viruses and give rise to the possibility that there may be as many as four distinct species of virus. Utilizing NGS sequencing technologies and proper phylogenetic practices will rapidly increase the solution to sustainable cassava production.en_US
dcterms.accessRightsOpen Accessen_US
dcterms.available2015-10-06en_US
dcterms.bibliographicCitationNdunguru, Joseph; Sseruwagi, Peter; Tairo, Fred; Stomeo, Francesca; Maina, Solomon; Djikeng, Appolinaire; Kehoe, Monica; Boykin, Laura M. 2015. Analyses of Twelve New Whole Genome Sequences of Cassava Brown Streak Viruses and Ugandan Cassava Brown Streak Viruses from East Africa: Diversity, Supercomputing and Evidence for Further Speciation. PLOS ONE 10: e0139321en_US
dcterms.extente0139321en_US
dcterms.issued2015-10-06en_US
dcterms.languageenen_US
dcterms.licenseCC-BY-4.0en_US
dcterms.publisherPublic Library of Scienceen_US
dcterms.subjectcassavaen_US
dcterms.subjectvirusesen_US
dcterms.subjectafricaen_US
dcterms.subjecteast africaen_US
dcterms.typeJournal Articleen_US

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