Analyses of Twelve New Whole Genome Sequences of Cassava Brown Streak Viruses and Ugandan Cassava Brown Streak Viruses from East Africa: Diversity, Supercomputing and Evidence for Further Speciation

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cg.contributor.affiliationDepartment of Agriculture and Food, Western Australiaen
cg.contributor.affiliationInternational Livestock Research Instituteen
cg.contributor.affiliationMikocheni Agricultural Research Instituteen
cg.contributor.affiliationUniversity of Western Australiaen
cg.contributor.donorBill & Melinda Gates Foundationen
cg.creator.identifierAppolinaire Djikeng: 0000-0001-9271-3419
cg.identifier.doihttps://doi.org/10.1371/journal.pone.0139321en
cg.issn1932-6203en
cg.issue10en
cg.journalPLOS ONEen
cg.volume10en
dc.contributor.authorNdunguru, Josephen
dc.contributor.authorSseruwagi, Peteren
dc.contributor.authorTairo, Freden
dc.contributor.authorStomeo, Francescaen
dc.contributor.authorMaina, Solomonen
dc.contributor.authorDjikeng, Appolinaireen
dc.contributor.authorKehoe, Monicaen
dc.contributor.authorBoykin, Laura M.en
dc.date.accessioned2023-03-10T14:36:33Zen
dc.date.available2023-03-10T14:36:33Zen
dc.identifier.urihttps://hdl.handle.net/10568/129485
dc.titleAnalyses of Twelve New Whole Genome Sequences of Cassava Brown Streak Viruses and Ugandan Cassava Brown Streak Viruses from East Africa: Diversity, Supercomputing and Evidence for Further Speciationen
dcterms.abstractCassava brown streak disease is caused by two devastating viruses, Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV) which are frequently found infecting cassava, one of sub-Saharan Africa’s most important staple food crops. Each year these viruses cause losses of up to $100 million USD and can leave entire families without their primary food source, for an entire year. Twelve new whole genomes, including seven of CBSV and five of UCBSV were uncovered in this research, doubling the genomic sequences available in the public domain for these viruses. These new sequences disprove the assumption that the viruses are limited by agro-ecological zones, show that current diagnostic primers are insufficient to provide confident diagnosis of these viruses and give rise to the possibility that there may be as many as four distinct species of virus. Utilizing NGS sequencing technologies and proper phylogenetic practices will rapidly increase the solution to sustainable cassava production.en
dcterms.accessRightsOpen Access
dcterms.available2015-10-06
dcterms.bibliographicCitationNdunguru, Joseph; Sseruwagi, Peter; Tairo, Fred; Stomeo, Francesca; Maina, Solomon; Djikeng, Appolinaire; Kehoe, Monica; Boykin, Laura M. 2015. Analyses of Twelve New Whole Genome Sequences of Cassava Brown Streak Viruses and Ugandan Cassava Brown Streak Viruses from East Africa: Diversity, Supercomputing and Evidence for Further Speciation. PLOS ONE 10: e0139321en
dcterms.extente0139321en
dcterms.issued2015-10-06
dcterms.languageen
dcterms.licenseCC-BY-4.0
dcterms.publisherPublic Library of Scienceen
dcterms.subjectcassavaen
dcterms.subjectvirusesen
dcterms.subjectafricaen
dcterms.subjecteast africaen
dcterms.typeJournal Article

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