Indirect genetic effects and inbreeding: Consequences of BLUP selection for socially affected traits on rate of inbreeding

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cg.contributor.affiliationWageningen University & Researchen
cg.contributor.crpLivestock and Fish
cg.howPublishedFormally Publisheden
cg.identifier.doihttps://doi.org/10.1186/1297-9686-46-39en
cg.isijournalISI Journalen
cg.issn1297-9686en
cg.issue1en
cg.journalGenetics Selection Evolutionen
cg.subject.ilriGENETICSen
cg.subject.ilriRESEARCHen
cg.subject.ilriFISHen
cg.volume46en
dc.contributor.authorHooi Ling Khawen
dc.contributor.authorPonzoni, R.W.en
dc.contributor.authorBijma, P.en
dc.date.accessioned2015-02-27T07:08:20Zen
dc.date.available2015-02-27T07:08:20Zen
dc.identifier.urihttps://hdl.handle.net/10568/56953
dc.titleIndirect genetic effects and inbreeding: Consequences of BLUP selection for socially affected traits on rate of inbreedingen
dcterms.abstractBackground Social interactions often occur among living organisms, including aquatic animals. There is empirical evidence showing that social interactions may genetically affect phenotypes of individuals and their group mates. In this context, the heritable effect of an individual on the phenotype of another individual is known as an Indirect Genetic Effect (IGE). Selection for socially affected traits may increase response to artificial selection, but also affect rate of inbreeding. Methods A simulation study was conducted to examine the effect of Best Linear Unbiased Prediction (BLUP) selection for socially affected traits on the rate of inbreeding. A base scenario without IGE and three alternative scenarios with different magnitudes of IGE were simulated. In each generation, 25 sires and 50 dams were mated, producing eight progeny per dam. The population was selected for 20 generations using BLUP. Individuals were randomly assigned to groups of eight members in each generation, with two families per group, each contributing four individuals. “Heritabilities” (for both direct and indirect genetic effects) were equal to 0.1, 0.3 or 0.5, and direct–indirect genetic correlations were −0.8, −0.4, 0, 0.4, or 0.8. The rate of inbreeding was calculated from generation 10 to 20. Results For the base scenario, the rates of inbreeding were 4.09, 2.80 and 1.95% for “heritabilities” of 0.1, 0.3 and 0.5, respectively. Overall, rates of inbreeding for the three scenarios with IGE ranged from 2.21 to 5.76% and were greater than for the base scenarios. The results show that social interaction within groups of two families increases the resemblance between estimated breeding values of relatives, which, in turn, increases the rate of inbreeding. Conclusion BLUP selection for socially affected traits increased the rate of inbreeding. To maintain inbreeding at an acceptable rate, a selection algorithm that restricts the increase in mean kinship, such as optimum contribution selection, is required.en
dcterms.accessRightsOpen Access
dcterms.audienceScientistsen
dcterms.bibliographicCitationHooi Ling Khaw, Ponzoni, R.W. and Bijma, P. 2014. Indirect genetic effects and inbreeding: Consequences of BLUP selection for socially affected traits on rate of inbreeding. Genetics Selection Evolution 46: 39en
dcterms.issued2014en
dcterms.languageen
dcterms.publisherSpringeren
dcterms.subjectresearchen
dcterms.subjectgenetic correlationen
dcterms.typeJournal Article

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