Ethiopian indigenous goats offer insights into past and recent demographic dynamics and local adaptation in sub-Saharan African goats
cg.authorship.types | CGIAR and developing country institute | en |
cg.authorship.types | CGIAR and advanced research institute | en |
cg.contributor.affiliation | Bahir Dar University | en |
cg.contributor.affiliation | Swedish University of Agricultural Sciences | en |
cg.contributor.affiliation | University of Natural Resources and Life Sciences, Vienna | en |
cg.contributor.affiliation | Inner Mongolia Agricultural University | en |
cg.contributor.affiliation | University of Queensland | en |
cg.contributor.affiliation | International Center for Agricultural Research in the Dry Areas | en |
cg.contributor.affiliation | Addis Ababa University | en |
cg.contributor.affiliation | International Livestock Research Institute | en |
cg.contributor.affiliation | University of Edinburgh | en |
cg.contributor.crp | Livestock | |
cg.contributor.donor | Africa Biosciences Challenge Fund | en |
cg.contributor.donor | Department of Foreign Affairs and Trade, Australia | en |
cg.contributor.donor | Syngenta Foundation for Sustainable Agriculture | en |
cg.contributor.donor | Bill & Melinda Gates Foundation | en |
cg.contributor.donor | Department for International Development, United Kingdom | en |
cg.contributor.donor | Swedish International Development Cooperation Agency | en |
cg.coverage.country | Ethiopia | |
cg.coverage.iso3166-alpha2 | ET | |
cg.coverage.region | Africa | |
cg.coverage.region | Eastern Africa | |
cg.creator.identifier | Getinet Mekuriaw Tarekegn: 0000-0001-7221-2473 | |
cg.creator.identifier | Aynalem: 0000-0001-5914-0487 | |
cg.creator.identifier | Barbara Rischkowsky: 0000-0002-0035-471X | |
cg.creator.identifier | Tadelle Dessie: 0000-0002-1630-0417 | |
cg.creator.identifier | Ally Okeyo Mwai: 0000-0003-2379-7801 | |
cg.creator.identifier | Joram Mwacharo: 0000-0001-6981-8140 | |
cg.creator.identifier | Appolinaire Djikeng: 0000-0001-9271-3419 | |
cg.howPublished | Formally Published | en |
cg.identifier.doi | https://doi.org/10.1111/eva.13118 | en |
cg.isijournal | ISI Journal | en |
cg.issn | 1752-4571 | en |
cg.issue | 7 | en |
cg.journal | Evolutionary Applications | en |
cg.reviewStatus | Peer Review | en |
cg.subject.ilri | ANIMAL BREEDING | en |
cg.subject.ilri | GOATS | en |
cg.subject.ilri | INDIGENOUS BREEDS | en |
cg.subject.ilri | SMALL RUMINANTS | en |
cg.volume | 14 | en |
dc.contributor.author | Mekuriaw, Getinet | en |
dc.contributor.author | Khayatzadeh, N. | en |
dc.contributor.author | Liu, B. | en |
dc.contributor.author | Osama, S. | en |
dc.contributor.author | Haile, Aynalem | en |
dc.contributor.author | Rischkowsky, Barbara A. | en |
dc.contributor.author | Zhang, W. | en |
dc.contributor.author | Tesfaye, K. | en |
dc.contributor.author | Dessie, Tadelle | en |
dc.contributor.author | Okeyo Mwai, Ally | en |
dc.contributor.author | Djikeng, Appolinaire | en |
dc.contributor.author | Mwacharo, Joram M. | en |
dc.date.accessioned | 2020-09-14T08:33:45Z | en |
dc.date.available | 2020-09-14T08:33:45Z | en |
dc.identifier.uri | https://hdl.handle.net/10568/109412 | |
dc.title | Ethiopian indigenous goats offer insights into past and recent demographic dynamics and local adaptation in sub-Saharan African goats | en |
dcterms.abstract | Knowledge on how adaptive evolution and human socio‐cultural and economic interests shaped livestock genomes particularly in sub‐Saharan Africa remains limited. Ethiopia is in a geographic region that has been critical in the history of African agriculture with ancient and diverse human ethnicity and bio‐climatic conditions. Using 52K genome‐wide data analysed in 646 individuals from 13 Ethiopian indigenous goat populations, we observed high levels of genetic variation. Although runs of homozygosity (ROH) were ubiquitous genome‐wide, there were clear differences in patterns of ROH length and abundance and in effective population sizes illustrating differences in genome homozygosity, evolutionary history, and management. Phylogenetic analysis incorporating patterns of genetic differentiation and gene flow with ancestry modelling highlighted past and recent intermixing and possible two deep ancient genetic ancestries that could have been brought by humans with the first introduction of goats in Africa. We observed four strong selection signatures that were specific to Arsi‐Bale and Nubian goats. These signatures overlapped genomic regions with genes associated with morphological, adaptation, reproduction and production traits due possibly to selection under environmental constraints and/or human preferences. The regions also overlapped uncharacterized genes, calling for a comprehensive annotation of the goat genome. Our results provide insights into mechanisms leading to genome variation and differentiation in sub‐Saharan Africa indigenous goats. | en |
dcterms.accessRights | Open Access | |
dcterms.audience | Scientists | en |
dcterms.available | 2021-06-15 | |
dcterms.bibliographicCitation | Mekuriaw, G., Khayatzadeh, N., Liu, B., Osama, S., Haile, A., Rischkowsky, B., Zhang, W., Tesfaye, K., Dessie, T., Okeyo, A.M., Djikeng, A. and Mwacharo, J.M. 2021. Ethiopian indigenous goats offer insights into past and recent demographic dynamics and local adaptation in sub-Saharan African goats. Evolutionary Applications 14(7):1716-1731. | en |
dcterms.extent | p. 1716-1731 | en |
dcterms.issued | 2021-07 | |
dcterms.language | en | |
dcterms.license | CC-BY-4.0 | |
dcterms.publisher | Wiley | en |
dcterms.subject | indigenous breeds | en |
dcterms.subject | goats | en |
dcterms.subject | small ruminants | en |
dcterms.subject | animal breeding | en |
dcterms.type | Journal Article |
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