Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet

Simple item page
cg.authorship.typesCGIAR and developing country instituteen
cg.authorship.typesCGIAR and advanced research instituteen
cg.contributor.affiliationSichuan Agricultural Universityen
cg.contributor.affiliationVirginia Techen
cg.contributor.affiliationUniversity of Georgiaen
cg.contributor.affiliationNovogene Bioinformatics Institute, Chinaen
cg.contributor.affiliationNanjing Agricultural Universityen
cg.contributor.affiliationSichuan Universityen
cg.contributor.affiliationUniversity of Floridaen
cg.contributor.affiliationInternational Livestock Research Instituteen
cg.contributor.affiliationInternational Crops Research Institute for the Semi-Arid Tropicsen
cg.contributor.affiliationValencia Polytechnic Universityen
cg.contributor.affiliationSichuan Animal Science Academy, Chinaen
cg.contributor.affiliationWuhan Universityen
cg.contributor.donorNational Natural Science Foundation of Chinaen
cg.contributor.donorCGIAR Trust Funden
cg.contributor.initiativeLivestock and Climate
cg.creator.identifierChris Jones: 0000-0001-9096-9728
cg.howPublishedFormally Publisheden
cg.identifier.doihttps://doi.org/10.1038/s41588-023-01302-4en
cg.isijournalISI Journalen
cg.issn1546-1718en
cg.issue3en
cg.journalNature Geneticsen
cg.reviewStatusPeer Reviewen
cg.subject.actionAreaResilient Agrifood Systems
cg.subject.ilriCROPSen
cg.subject.impactAreaClimate adaptation and mitigation
cg.volume55en
dc.contributor.authorHaidong Yanen
dc.contributor.authorMin Sunen
dc.contributor.authorZhongren Zhangen
dc.contributor.authorYarong Jinen
dc.contributor.authorAiling Zhangen
dc.contributor.authorChuang Linen
dc.contributor.authorBingchao Wuen
dc.contributor.authorMin Heen
dc.contributor.authorBin Xuen
dc.contributor.authorJing Wangen
dc.contributor.authorPeng Qinen
dc.contributor.authorMendieta, J.P.en
dc.contributor.authorGang Nieen
dc.contributor.authorJianping Wangen
dc.contributor.authorJones, Christopher S.en
dc.contributor.authorGuangyan Fengen
dc.contributor.authorSrivastava, R.K.en
dc.contributor.authorXinquan Zhangen
dc.contributor.authorBombarely, A.en
dc.contributor.authorDan Luoen
dc.contributor.authorLong Jinen
dc.contributor.authorYuanying Pengen
dc.contributor.authorXiaoshan Wangen
dc.contributor.authorYang Jien
dc.contributor.authorShilin Tianen
dc.contributor.authorLinkai Huangen
dc.date.accessioned2023-03-07T14:09:04Zen
dc.date.available2023-03-07T14:09:04Zen
dc.identifier.urihttps://hdl.handle.net/10568/129215
dc.titlePangenomic analysis identifies structural variation associated with heat tolerance in pearl milleten
dcterms.abstractPearl millet is an important cereal crop worldwide and shows superior heat tolerance. Here, we developed a graph-based pan-genome by assembling ten chromosomal genomes with one existing assembly adapted to different climates worldwide and captured 424,085 genomic structural variations (SVs). Comparative genomics and transcriptomics analyses revealed the expansion of the RWP-RK transcription factor family and the involvement of endoplasmic reticulum (ER)-related genes in heat tolerance. The overexpression of one RWP-RK gene led to enhanced plant heat tolerance and transactivated ER-related genes quickly, supporting the important roles of RWP-RK transcription factors and ER system in heat tolerance. Furthermore, we found that some SVs affected the gene expression associated with heat tolerance and SVs surrounding ER-related genes shaped adaptation to heat tolerance during domestication in the population. Our study provides a comprehensive genomic resource revealing insights into heat tolerance and laying a foundation for generating more robust crops under the changing climate.en
dcterms.accessRightsOpen Access
dcterms.audienceScientistsen
dcterms.available2023-03-02
dcterms.bibliographicCitationHaidong Yan, Min Sun, Zhongren Zhang, Yarong Jin, Ailing Zhang, Chuang Lin, Bingchao Wu, Min He, Bin Xu, Jing Wang, Peng Qin, Mendieta, J.P., Gang Nie, Jianping Wang, Jones, C.S., Guangyan Feng, Srivastava, R.K., Xinquan Zhang, Bombarely, A., Dan Luo, Long Jin, Yuanying Peng, Xiaoshan Wang, Yang Ji, Shilin Tian and Linkai Huang. 2023. Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet. Nature Genetics 55:507–518.en
dcterms.extentp. 507-518en
dcterms.issued2023-03
dcterms.languageen
dcterms.licenseCC-BY-4.0
dcterms.publisherSpringeren
dcterms.subjectmilletsen
dcterms.subjectpearl milleten
dcterms.subjectheat toleranceen
dcterms.typeJournal Article

Files

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ILRI articles in journals
CGIAR Initiative on Livestock and Climate
ILRI feed and forage development program outputs