Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle

cg.identifier.doihttps://doi.org/10.1006/expr.1995.1104en
cg.issn0014-4894en
cg.issue2en
cg.journalExperimental Parasitologyen
cg.subject.ilriANIMAL DISEASESen
cg.subject.ilriDISEASE CONTROLen
cg.subject.ilriLIVESTOCKen
cg.volume81en
dc.contributor.authorLutje, V.en
dc.contributor.authorMertens, B.en
dc.contributor.authorBoulange, A.F.en
dc.contributor.authorWilliams, D.J.L.en
dc.contributor.authorAuthié, Edithen
dc.date.accessioned2013-05-06T07:00:58Zen
dc.date.available2013-05-06T07:00:58Zen
dc.identifier.urihttps://hdl.handle.net/10568/28607
dc.titleTrypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattleen
dcterms.abstractT-cell-mediated immune responses to defined antigens of Trypanosoma congolense were measured in cattle undergoing primary infection. The antigens used were the variable surface glycoprotein and two invariant antigens, a 33-kDa cysteine protease (congopain) and a recombinant form of a 69-kDa heat-shock protein. Proliferative responses were highest during the second week postinfection and were detected in cells obtained from the lymph node draining the site of infection but not in peripheral blood mononuclear cells. Production of IL-2 and IFN- was measured in supernatants from antigen-stimulated lymph node cell cultures. Expression of IL-2, IL-4, and IFN- mRNA was detected in antigen-stimulated lymph node cells by reverse transcription-polymerase chain amplification.en
dcterms.accessRightsLimited Access
dcterms.bibliographicCitationExperimental Parasitology;81(2): 154-164en
dcterms.extentp. 154-164en
dcterms.issued1995-09
dcterms.languageen
dcterms.licenseCopyrighted; all rights reserved
dcterms.publisherElsevieren
dcterms.subjecttrypanosoma congolenseen
dcterms.subjectinterleukinen
dcterms.subjectinfectionen
dcterms.subjectcattleen
dcterms.subjectanimal diseasesen
dcterms.subjectimmunologyen
dcterms.subjectparasitologyen
dcterms.subjectinfectious diseasesen
dcterms.typeJournal Article

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