African suid genomes provide insights into the local adaptation to diverse African environments

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cg.authorship.typesCGIAR and developing country instituteen
cg.contributor.affiliationChinese Academy of Sciencesen
cg.contributor.affiliationBayero Universityen
cg.contributor.affiliationNorthwestern Polytechnical Universityen
cg.contributor.affiliationNational Park Service Headquarter, Nigeriaen
cg.contributor.affiliationInternational Livestock Research Instituteen
cg.contributor.affiliationChinese Academy of Agricultural Sciencesen
cg.contributor.affiliationObafemi Awolowo Universityen
cg.contributor.affiliationUniversity of Ibadanen
cg.contributor.affiliationFederal University of Technology, Owerri, Nigeriaen
cg.contributor.affiliationUniversity of Agriculture, Makurdien
cg.contributor.affiliationTaraba State Ministry of Agriculture and Natural Resources, Nigeriaen
cg.contributor.affiliationNational Veterinary Research Institute, Nigeriaen
cg.contributor.affiliationKenya Wildlife Serviceen
cg.contributor.affiliationYunnan Universityen
cg.contributor.crpLivestocken
cg.contributor.donorChinese Academy of Sciencesen
cg.contributor.donorNational Natural Science Foundation of Chinaen
cg.contributor.donorNational Key Research and Development Program, Chinaen
cg.contributor.donorSino-Africa Joint Research Centeren
cg.contributor.donorNorthwestern Polytechnical Universityen
cg.contributor.donorSouthwest Research Center for Pig Molecular Breeding and Translational Medicineen
cg.contributor.donorSpring City Plan: the High-level Talent Promotion and Training Project of Kunmingen
cg.contributor.donorYunnan Revitalization Talent Support Programen
cg.contributor.donorGovernment of Chinaen
cg.coverage.regionAfricaen
cg.creator.identifierRichard Bishop: 0000-0002-3720-9970en
cg.creator.identifierAbworo: 0000-0003-0689-823Xen
cg.howPublishedFormally Publisheden
cg.identifier.doihttps://doi.org/10.1093/molbev/msac256en
cg.isijournalISI Journalen
cg.issn0737-4038en
cg.issue12en
cg.journalMolecular Biology and Evolutionen
cg.reviewStatusPeer Reviewen
cg.subject.ilriANIMAL DISEASESen
cg.subject.ilriASFen
cg.subject.ilriGENETICSen
cg.subject.ilriPIGSen
cg.volume39en
dc.contributor.authorHai-Bing Xieen
dc.contributor.authorChen Yanen
dc.contributor.authorAdeola, A.C.en
dc.contributor.authorKun Wangen
dc.contributor.authorCui-Ping Huangen
dc.contributor.authorMing-Min Xuen
dc.contributor.authorQiang Qiuen
dc.contributor.authorXue Yinen
dc.contributor.authorChen-Yu Fanen
dc.contributor.authorYun-Fei Maen
dc.contributor.authorTing-Ting Yinen
dc.contributor.authorYun Gaoen
dc.contributor.authorJia-Kun Dengen
dc.contributor.authorOkeyoyin, A.O.en
dc.contributor.authorOluwole, O.O.en
dc.contributor.authorOmotosho, O.en
dc.contributor.authorOkoro, V.M.O.en
dc.contributor.authorOmitogun, O.G.en
dc.contributor.authorDawuda, P.M.en
dc.contributor.authorOlaogun, S.C.en
dc.contributor.authorNneji, L.M.en
dc.contributor.authorAyoola, A.O.en
dc.contributor.authorSanke, O.J.en
dc.contributor.authorLuka, P.D.en
dc.contributor.authorOkoth, Edward A.en
dc.contributor.authorLekolool, I.en
dc.contributor.authorMijele, D.en
dc.contributor.authorBishop, Richard P.en
dc.contributor.authorJianlin Hanen
dc.contributor.authorWen Wangen
dc.contributor.authorMin-Sheng Pengen
dc.contributor.authorYa-Ping Zhangen
dc.date.accessioned2022-11-28T10:40:58Zen
dc.date.available2022-11-28T10:40:58Zen
dc.identifier.urihttps://hdl.handle.net/10568/125687
dc.titleAfrican suid genomes provide insights into the local adaptation to diverse African environmentsen
dcterms.abstractAfrican wild suids consist of several endemic species that represent ancient members of the family Suidae and have colonized diverse habitats on the African continent. However, limited genomic resources for African wild suids hinder our understanding of their evolution and genetic diversity. In this study, we assembled high-quality genomes of a common warthog (Phacochoerus africanus), a red river hog (Potamochoerus porcus), as well as an East Asian Diannan small-ear pig (Sus scrofa). Phylogenetic analysis showed that common warthog and red river hog diverged from their common ancestor around the Miocene/Pliocene boundary, putatively predating their entry into Africa. We detected species-specific selective signals associated with sensory perception and interferon signaling pathways in common warthog and red river hog, respectively, which contributed to their local adaptation to savannah and tropical rainforest environments, respectively. The structural variation and evolving signals in genes involved in T-cell immunity, viral infection, and lymphoid development were identified in their ancestral lineage. Our results provide new insights into the evolutionary histories and divergent genetic adaptations of African suids.en
dcterms.accessRightsOpen Accessen
dcterms.audienceScientistsen
dcterms.available2022-11-22en
dcterms.bibliographicCitationXie, H.-B., Yan, C., Adeola, A.C., Wang, K., Huang, C.-P., Xu, M.-M., Qiu, Q., Yin, X., Fan, C.-Y., Ma, Y.-F., Yin, T.-T., Gao, Y., Deng, J.-K., Okeyoyin, A.O., Oluwole, O.O., Omotosho, O., Okoro, V.M.O., Omitogun, O.G., Dawuda, P.M., Olaogun, S.C., Nneji, L.M., Ayoola, A.O., Sanke, O.J., Luka, P.D., Okoth, E., Lekolool, I., Mijele, D., Bishop, R.P., Han, J., Wang, W., Peng, M.-S. and Zhang, Y.-P. 2022. African suid genomes provide insights into the local adaptation to diverse African environments. Molecular Biology and Evolution 39(12): msac256.en
dcterms.extentmsac256en
dcterms.issued2022-12-05en
dcterms.languageenen
dcterms.licenseCC-BY-NC-4.0en
dcterms.publisherOxford University Pressen
dcterms.subjectsuidaeen
dcterms.subjectswineen
dcterms.subjectpig breedsen
dcterms.subjectgenomesen
dcterms.subjectafrican swine feveren
dcterms.subjectgeneticsen
dcterms.subjectmolecular biologyen
dcterms.typeJournal Articleen

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