Theileria parva: influence of vector, parasite and host relationships on the epidemiology of theileriosis in southern Africa

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cg.contributor.affiliationInternational Laboratory for Research on Animal Diseasesen
cg.contributor.affiliationKenya Agricultural Research Instituteen
cg.coverage.countryMozambique
cg.coverage.countrySouth Africa
cg.coverage.iso3166-alpha2MZ
cg.coverage.iso3166-alpha2ZA
cg.coverage.regionEastern Africa
cg.coverage.regionSouthern Africa
cg.identifier.doihttps://doi.org/10.1017/s0031182000064295en
cg.issn0031-1820en
cg.issn1469-8161en
cg.issue3en
cg.journalParasitologyen
cg.volume102en
dc.contributor.authorNorval, R.A.I.en
dc.contributor.authorLawrence, J. A.en
dc.contributor.authorYoung, A.S.en
dc.contributor.authorPerry, Brian D.en
dc.contributor.authorDolan, T. T.en
dc.contributor.authorScott, J.en
dc.date.accessioned2024-09-11T09:26:02Zen
dc.date.available2024-09-11T09:26:02Zen
dc.identifier.urihttps://hdl.handle.net/10568/152135
dc.titleTheileria parva: influence of vector, parasite and host relationships on the epidemiology of theileriosis in southern Africaen
dcterms.abstractThe protozoan parasite Theileria parva, transmitted by the ixodid tick Rhipicephalus appendiculatus, is the cause of East Coast fever (ECF) and the related syndromes of Corridor disease and January disease in cattle of eastern, central and southern Africa. It is likely that buffalo (Syncerus caffer) are the natural host of T. parva. In eastern and southern Africa, there exist both buffalo-adapted and cattle-adapted T. parva. Disease caused by buffalo-adapted parasites is called Corridor disease, and that caused by cattle-adapted parasites is termed East Coast fever. In eastern Africa, it has been shown experimentally that buffalo-adapted T. parva can, after serial passage in cattle, become adapted to cattle, in which it can then be maintained and cause ECF. This adaptation has been termed transformation. The transformation of buffalo-adapted T. parva to a cattle-adapted parasite has not been reported in southern Africa, and ECF, eradicated from South Africa, Swaziland and southern Mozambique by 1960, has not reappeared in the subcontinent. This paper discusses the possible reasons for this, and hypothesizes that vector population dynamics and the susceptibility of the vector population to infection with T. parva are among the most important factors which influence the expression of ECF as a disease entity, and the likelihood of transformation occurring. It also considers the possibility that disappearance of ECF from southern Africa resulted from the extinction, as a result of vigorous control measures and unfavourable climatic conditions, of non-diapausing populations of R. appendiculatus that may have been introduced from eastern Africa with cattle imported in 1901.en
dcterms.accessRightsLimited Access
dcterms.available2009-04-06
dcterms.bibliographicCitationNorval, R. A. I., Lawrence, J. A., Young, A. S., Perry, B. D., Dolan, T. T., & Scott, J. (1991). Theileria parva: influence of vector, parasite and host relationships on the epidemiology of theileriosis in southern Africa. Parasitology, 102(3), 347–356. https://doi.org/10.1017/s0031182000064295en
dcterms.extentpp. 347-356en
dcterms.issued1991-06
dcterms.languageen
dcterms.licenseCopyrighted; all rights reserved
dcterms.publisherCambridge University Pressen
dcterms.subjectcattleen
dcterms.subjectadaptationen
dcterms.subjectepidemiologyen
dcterms.subjecttheileria parvaen
dcterms.subjecteast coast feveren
dcterms.subjectinfectionen
dcterms.subjecttransformationen
dcterms.subjectparasitesen
dcterms.subjectpopulationen
dcterms.subjectpopulation dynamicsen
dcterms.subjectrhipicephalus appendiculatusen
dcterms.subjectdynamicsen
dcterms.subjecttheileriosisen
dcterms.subjectparasiteen
dcterms.subjectrelationshipsen
dcterms.subjectsusceptibilityen
dcterms.typeJournal Article

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