Linkage mapping of the bovine lysosomal alphamannosidase (MANB) gene

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cg.creator.identifierOlivier Hanotte: 0000-0002-2877-4767
cg.identifier.doihttps://doi.org/10.1046/j.1365-2052.1999.00404-3.xen
cg.issn0268-9146en
cg.issue3en
cg.journalAnimal Geneticsen
cg.subject.ilriCATTLEen
cg.subject.ilriLIVESTOCKen
cg.subject.ilriGENETICSen
cg.volume30en
dc.contributor.authorGelhaus, A.en
dc.contributor.authorHanotte, Olivier H.en
dc.contributor.authorHorstmann, R.D.en
dc.contributor.authorTeale, A.J.en
dc.date.accessioned2013-06-11T09:26:04Zen
dc.date.available2013-06-11T09:26:04Zen
dc.identifier.urihttps://hdl.handle.net/10568/30064
dc.titleLinkage mapping of the bovine lysosomal alphamannosidase (MANB) geneen
dcterms.abstractLysosomal alpha-mannosidase is involved in the metabolism of mannoses in oligosaccharides in lysosomes. Deficiency of alpha-mannosidase, alpha-mannosidosis, has been described as an autosomal recessive storage disease in angus cattle, Galloway cattle and in cats. It is caused by non-synonymous substitutions in the encoding gene (MANB). Primers for MANB were designed from a bovine sequence (Gen Bank accession number U97686) and amplified a 316-bp fragment comprising intron 2 and adjacent exonic sequences. This paper discusses PCR primers, PCR conditions and polymorphism detection; and allele frequencies, inheritance and chromosomal location.en
dcterms.accessRightsLimited Access
dcterms.available2001-12-24
dcterms.bibliographicCitationAnimal Genetics;30: 227-228en
dcterms.extentp. 227-228en
dcterms.issued1999-06
dcterms.languageen
dcterms.licenseCopyrighted; all rights reserved
dcterms.publisherWileyen
dcterms.subjectbovidaeen
dcterms.subjectgenesen
dcterms.subjectgenetic mapsen
dcterms.subjectlysozymeen
dcterms.typeJournal Article

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