Household socio-economic position and individual infectious disease risk in rural Kenya

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cg.authorship.typesCGIAR and developing country instituteen_US
cg.authorship.typesCGIAR and advanced research instituteen_US
cg.contributor.affiliationUniversity of Edinburghen_US
cg.contributor.affiliationInternational Livestock Research Instituteen_US
cg.contributor.affiliationUniversity of Glasgowen_US
cg.contributor.affiliationUnited States International Universityen_US
cg.contributor.affiliationKenya Medical Research Instituteen_US
cg.contributor.affiliationUniversity of Liverpoolen_US
cg.contributor.crpAgriculture for Nutrition and Healthen_US
cg.contributor.donorBiotechnology and Biological Sciences Research Council, United Kingdomen_US
cg.contributor.donorMedical Research Council, United Kingdomen_US
cg.contributor.donorWellcome Trusten_US
cg.coverage.countryKenyaen_US
cg.coverage.iso3166-alpha2KEen_US
cg.coverage.regionAfricaen_US
cg.coverage.regionEastern Africaen_US
cg.creator.identifierWilliam de Glanville: 0000-0003-2474-0356en_US
cg.creator.identifierLian Thomas: 0000-0001-8447-1210en_US
cg.creator.identifierElizabeth Cook: 0000-0001-6081-8363en_US
cg.creator.identifierMark Bronsvoort: 0000-0002-3271-8485en_US
cg.creator.identifierEric M. Fèvre: 0000-0001-8931-4986en_US
cg.howPublishedFormally Publisheden_US
cg.identifier.doihttps://doi.org/10.1038/s41598-019-39375-zen_US
cg.isijournalISI Journalen_US
cg.issn2045-2322en_US
cg.issue1en_US
cg.journalScientific Reportsen_US
cg.reviewStatusPeer Reviewen_US
cg.subject.ilriAGRI-HEALTHen_US
cg.subject.ilriHEALTHen_US
cg.subject.ilriZOONOTIC DISEASESen_US
cg.volume9en_US
dc.contributor.authorGlanville, William A. deen_US
dc.contributor.authorThomas, Lian F.en_US
dc.contributor.authorCook, Elizabeth A.J.en_US
dc.contributor.authorBronsvoort, B.M. de C.en_US
dc.contributor.authorWamae, N.C.en_US
dc.contributor.authorKariuki, S.en_US
dc.contributor.authorFèvre, Eric M.en_US
dc.date.accessioned2019-03-05T13:56:25Zen_US
dc.date.available2019-03-05T13:56:25Zen_US
dc.identifier.urihttps://hdl.handle.net/10568/100114en_US
dc.titleHousehold socio-economic position and individual infectious disease risk in rural Kenyaen_US
dcterms.abstractThe importance of household socio-economic position (SEP) in shaping individual infectious disease risk is increasingly recognised, particularly in low income settings. However, few studies have measured the extent to which this association is consistent for the range of pathogens that are typically endemic among the rural poor in the tropics. This cross-sectional study assessed the relationship between SEP and human infection within a single community in western Kenya using a set of pathogens with diverse transmission routes. The relationships between household SEP and individual infection with Plasmodium falciparum, hookworm (Ancylostoma duodenale and/or Necator americanus), Entamoeba histolytica/dispar, Mycobacterium tuberculosis, and HIV, and co-infections between hookworm, P. falciparum and E. histolytica/dispar, were assessed using multivariable logistic and multinomial regression. Individuals in households with the lowest SEP were at greatest risk of infection with P. falciparum, hookworm and E. histolytica/dispar, as well as co-infection with each pathogen. Infection with M. tuberculosis, by contrast, was most likely in individuals living in households with the highest SEP. There was no evidence of a relationship between individual HIV infection and household SEP. We demonstrate the existence of a household socio-economic gradient within a rural farming community in Kenya which impacts upon individual infectious disease risk. Structural adjustments that seek to reduce poverty, and therefore the socio-economic inequalities that exist in this community, would be expected to substantially reduce overall infectious disease burden. However, policy makers and researchers should be aware that heterogeneous relationships can exist between household SEP and infection risk for different pathogens in low income settings.en_US
dcterms.accessRightsOpen Accessen_US
dcterms.audienceScientistsen_US
dcterms.available2019-02-27en_US
dcterms.bibliographicCitationGlanville, W.A. de, Thomas, L.F., Cook, E.A.J., Bronsvoort, B.M. de C., Wamae, N.C., Kariuki, S. and Fèvre, E.M. 2019. Household socio-economic position and individual infectious disease risk in rural Kenya. Scientific Reports 9: 2972.en_US
dcterms.issued2019-02-27en_US
dcterms.languageenen_US
dcterms.licenseCC-BY-4.0en_US
dcterms.publisherSpringeren_US
dcterms.subjectzoonosesen_US
dcterms.subjecthealthen_US
dcterms.typeJournal Articleen_US

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