Prevalence and phylogenetic analysis of hepatitis E virus in pigs in Vietnam

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cg.authorship.typesCGIAR and developing country instituteen
cg.authorship.typesCGIAR and advanced research instituteen
cg.contributor.affiliationInternational Livestock Research Instituteen
cg.contributor.affiliationNational Institute of Veterinary Research, Vietnamen
cg.contributor.affiliationUniversity of Greenwichen
cg.contributor.affiliationUniversity of Prince Edward Islanden
cg.contributor.affiliationRakuno Gakuen Universityen
cg.contributor.crpAgriculture for Nutrition and Health
cg.contributor.crpLivestock
cg.coverage.countryVietnam
cg.coverage.iso3166-alpha2VN
cg.coverage.regionAsia
cg.coverage.regionSouth-eastern Asia
cg.creator.identifierHu Suk Lee: 0000-0002-8731-9836
cg.creator.identifierHung Nguyen-Viet: 0000-0003-1549-2733
cg.creator.identifierDelia Grace: 0000-0002-0195-9489
cg.howPublishedFormally Publisheden
cg.identifier.doihttps://doi.org/10.1186/s12917-020-02537-7en
cg.isijournalISI Journalen
cg.issn1746-6148en
cg.issue1en
cg.journalBMC Veterinary Researchen
cg.reviewStatusPeer Reviewen
cg.subject.ilriANIMAL DISEASESen
cg.subject.ilriPIGSen
cg.volume16en
dc.contributor.authorHu Suk Leeen
dc.contributor.authorDuy Tung Daoen
dc.contributor.authorVuong Nghia Buien
dc.contributor.authorNgoc Anh Buien
dc.contributor.authorThanh Duy Leen
dc.contributor.authorHung Nguyen-Vieten
dc.contributor.authorGrace, Deliaen
dc.contributor.authorThakur, K.K.en
dc.contributor.authorHagiwara, K.en
dc.date.accessioned2020-09-21T12:02:08Zen
dc.date.available2020-09-21T12:02:08Zen
dc.identifier.urihttps://hdl.handle.net/10568/109554
dc.titlePrevalence and phylogenetic analysis of hepatitis E virus in pigs in Vietnamen
dcterms.abstractHepatitis E virus (HEV) is a zoonotic disease and has been reported around the world. The main objective of this study was to evaluate the sero-prevalence and phylogenetic analysis of HEV in Vietnam. Pig blood and fecal pooled samples were collected to assess the prevalence of HEV. We assessed the true prevalence (TP) of HEV from apparent prevalence (AP) by taking into account the sensitivity and specificity of diagnostic tests using a Bayesian approach. For phylogenetic analysis, the data compared with worldwide HEV reference strains including all eight genotypes (G1-G8) which were identified in previous study.A total of 475 sera and 250 fecal pooled samples were collected at slaughterhouses and pig farms from five provinces, in Viet Nam. Overall, the sero-AP of HEV was 58.53% (95% confidence interval: 53.95–62.70) while the sero-TP was slightly higher (65.43, 95% credible interval: 47.19–84.70). In terms of pooled samples, overall, the RNA-AP was 6.80% (95% confidence interval: 4.01–10.66). One strain in Hanoi, two strains in Dak Lak, seven strains in An Giang, four strains in Son La and two strains in Nghe An were isolated. The phylogenetic tree demonstrated that 19 Vietnamese strains were clustered into HEV 3 and 4.This study provided evidence that HEV is circulating in domestic pigs in Vietnam. From a public health perspective, it is very important to raise public awareness for high-risk groups (e.g. slaughterhouse workers, pig traders, farmers and market sellers) who have more opportunities to come in contact with pig and contaminated meats.en
dcterms.accessRightsOpen Access
dcterms.audienceScientistsen
dcterms.available2020-09-14
dcterms.bibliographicCitationHu Suk Lee, Duy Tung Dao, Vuong Nghia Bui, Ngoc Anh Bui, Thanh Duy Le, Hung Nguyen-Viet, Grace, D., Thakur, K.K. and Hagiwara, K. 2020. Prevalence and phylogenetic analysis of hepatitis E virus in pigs in Vietnam. BMC Veterinary Research 16: 333.en
dcterms.issued2020-12
dcterms.languageen
dcterms.licenseCC-BY-4.0
dcterms.publisherSpringeren
dcterms.subjecthepatitisen
dcterms.subjectswineen
dcterms.subjectanimal diseasesen
dcterms.typeJournal Article

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