Vitamin A intake and infection are associated with plasma retinol among pre-school children in rural Zambia
| cg.authorship.types | CGIAR single centre | en |
| cg.contributor.crp | Agriculture for Nutrition and Health | |
| cg.coverage.country | Zambia | |
| cg.coverage.iso3166-alpha2 | ZM | |
| cg.coverage.region | Southern Africa | |
| cg.coverage.region | Sub-Saharan Africa | |
| cg.coverage.region | Africa | |
| cg.coverage.region | Eastern Africa | |
| cg.identifier.doi | https://doi.org/10.1017/s1368980012000924 | en |
| cg.identifier.project | IFPRI - HarvestPlus | |
| cg.identifier.publicationRank | B | |
| cg.isijournal | ISI Journal | en |
| cg.issn | 1368-9800 | en |
| cg.issn | 1475-2727 | en |
| cg.issue | 9 | en |
| cg.journal | Public Health Nutrition | en |
| cg.reviewStatus | Peer Review | en |
| cg.volume | 15 | en |
| dc.contributor.author | Hotz, Christine | en |
| dc.contributor.author | Chileshe, Justin | en |
| dc.contributor.author | Siamusantu, Ward | en |
| dc.contributor.author | Palaniappan, Uma | en |
| dc.contributor.author | Kafwembe, Emmanuel | en |
| dc.date.accessioned | 2024-10-01T13:55:36Z | en |
| dc.date.available | 2024-10-01T13:55:36Z | en |
| dc.identifier.uri | https://hdl.handle.net/10568/153077 | |
| dc.title | Vitamin A intake and infection are associated with plasma retinol among pre-school children in rural Zambia | en |
| dcterms.abstract | To determine the prevalence of vitamin A deficiency, infection and adequacy of vitamin A intakes among Zambian children, and the contribution of dietary vitamin A and infection to vitamin A status.A cross-sectional survey of vitamin A intakes by the 24 h recall method, vitamin A status by plasma retinol and the modified relative dose-response test, and infection by acute-phase proteins.Rural communities in Central and Eastern Provinces of Zambia.Children 2–5 years of age.The prevalence of vitamin A deficiency was 56 % by plasma retinol, 48 % with infection-adjusted plasma retinol and 22 % by the modified relative dose-response test. The majority of children (61 %) had a current infection. Vitamin A intakes were relatively high (331 to 585 μg retinol activity equivalents/d in the harvest/early post-harvest and late post-harvest seasons, respectively) and the prevalence of inadequate intakes was <1 % when compared with the Estimated Average Requirement (210 and 275 μg retinol activity equivalents/d for children aged 1–3 and 4–8 years, respectively). Elevated α-1-acid glycoprotein was negatively associated with plasma retinol (P< 0·0 0 1) and vitamin A intake was positively associated with plasma retinol (P< 0·05), but only when estimated assuming a 26:1 retinol equivalence for provitamin A from green and yellow vegetables.Infection and vitamin A intakes were significant determinants of plasma retinol. We cannot conclude which indicator more accurately represents the true vitamin A status of the population. Reasons for the persistent high prevalence of vitamin A deficiency in the presence of adequate vitamin A intakes are unclear, but the high rates of infection may play a role. | en |
| dcterms.accessRights | Limited Access | |
| dcterms.available | 2012-03-23 | |
| dcterms.bibliographicCitation | Hotz, Christine; Chileshe, Justin; Siamusantu, Ward; Palaniappan, Uma; Kafwembe, Emmanuel 2012. Vitamin A intake and infection are associated with plasma retinol among pre-school children in rural Zambia. Public Health Nutrition 15(9): 1688-1696 | en |
| dcterms.extent | pp. 1688-1696 | en |
| dcterms.issued | 2012-09 | |
| dcterms.language | en | |
| dcterms.license | Copyrighted; all rights reserved | |
| dcterms.publisher | Cambridge University Press | en |
| dcterms.replaces | https://ebrary.ifpri.org/digital/collection/p15738coll5/id/3516 | en |
| dcterms.type | Journal Article |