A comparative study of major histocompatibility complex antigens in East African and European cattle breeds

cg.coverage.regionAfricaen
cg.coverage.regionEastern Africaen
cg.creator.identifierStephen J Kemp: 0000-0003-4041-1720en
cg.identifier.doihttps://doi.org/10.1111/j.1365-2052.1988.tb00784.xen
cg.issn0268-9146en
cg.issue1en
cg.journalAnimal Geneticsen
cg.subject.ilriANIMAL DISEASESen
cg.subject.ilriDISEASE CONTROLen
cg.subject.ilriLIVESTOCKen
cg.subject.ilriCATTLEen
cg.volume19en
dc.contributor.authorKemp, Stephen J.en
dc.contributor.authorSpooner, R.L.en
dc.contributor.authorTeale, A.J.en
dc.date.accessioned2013-05-06T07:00:10Zen
dc.date.available2013-05-06T07:00:10Zen
dc.identifier.urihttps://hdl.handle.net/10568/28216
dc.titleA comparative study of major histocompatibility complex antigens in East African and European cattle breedsen
dcterms.abstractSummary.An account is given of the serologically defined class I specificities encoded by the bovine MHC (expressed as the BoLA system) in two populations of African cattle and in European breeds.The BoLA typing was performed using alloantisera raised against tissue antigens of both European and African breeds of cattle. All of the specificities agreed in the first two international BoLA workshops were found in the African cattle, although there were significant differences in the frequency of some specificities between the African and European animals. Many of the European antisera, which are operationally monospecific in Bos taurus cattle, were multispecific in the African animals.Subgroups of two specificities (w8 and w10) were demonstrated. Five new BoLA‐A locus alleles were detected by means of antisera raised against alloantigens of African cattle. Two of these occurred at an extremely high frequency in the African populations; one being unique to these cattle. Monoclonal antibodies proved to be useful typing reagents, particularly in the elucidation of subgroups.en
dcterms.accessRightsLimited Accessen
dcterms.available2009-04-24en
dcterms.bibliographicCitationAnimal Genetics;19: 17-29en
dcterms.extentp. 17-29en
dcterms.issued1988en
dcterms.languageenen
dcterms.licenseCopyrighted; all rights reserveden
dcterms.publisherWileyen
dcterms.subjecteuropeen
dcterms.subjectantigensen
dcterms.subjectcattleen
dcterms.subjectbreedsen
dcterms.subjectmajor histocompatibility complexen
dcterms.typeJournal Articleen

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