Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays

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cg.creator.identifierStephen J Kemp: 0000-0003-4041-1720
cg.identifier.doihttps://doi.org/10.1186/1471-2164-9-317en
cg.issn1471-2164en
cg.issue1en
cg.journalBMC Genomicsen
cg.subject.ilriGENETICSen
cg.subject.ilriLIVESTOCKen
cg.volume9en
dc.contributor.authorRennie, C.en
dc.contributor.authorNoyes, H.A.en
dc.contributor.authorKemp, Stephen J.en
dc.contributor.authorHulme, H.en
dc.contributor.authorBrass, A.en
dc.contributor.authorHoyle, D.C.en
dc.date.accessioned2010-08-07T12:07:26Zen
dc.date.available2010-08-07T12:07:26Zen
dc.identifier.urihttps://hdl.handle.net/10568/2202
dc.titleStrong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarraysen
dcterms.abstractMicroarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are known to affect the stability of the probe-target duplex, and hence the strength of the observed signals from microarrays.en
dcterms.accessRightsOpen Access
dcterms.available2008-07-03
dcterms.bibliographicCitationRennie, C.; Noyes, H.A.; Kemp, S.J.; Hulme, H.; Brass, A.; Hoyle, D.C. 2008. Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays. BMC Genomics 9:317.en
dcterms.issued2008-12
dcterms.languageen
dcterms.publisherSpringeren
dcterms.subjectgeneticsen
dcterms.subjectlivestocken
dcterms.typeJournal Article

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