Acetyldiaminobutanoic acid, a potential lathyrogenic amino acid in leaves of Acacia angustissima

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cg.creator.identifierJean Hanson: 0000-0002-3648-2641
cg.identifier.doihttps://doi.org/10.1002/jsfa.960en
cg.issn0022-5142en
cg.issue15en
cg.journalJournal of the Science of Food and Agricultureen
cg.subject.ilriCATTLEen
cg.subject.ilriLIVESTOCKen
cg.subject.ilriANIMAL FEEDINGen
cg.subject.ilriFEEDSen
cg.volume81en
dc.contributor.authorReed, J.D.en
dc.contributor.authorGebre-Mariam, G.en
dc.contributor.authorRobinson, C.J.en
dc.contributor.authorHanson, Jeanen
dc.contributor.authorOdenyo, A.A.en
dc.contributor.authorTreichel, P.M.en
dc.date.accessioned2013-07-03T05:25:56Zen
dc.date.available2013-07-03T05:25:56Zen
dc.identifier.urihttps://hdl.handle.net/10568/33022
dc.titleAcetyldiaminobutanoic acid, a potential lathyrogenic amino acid in leaves of Acacia angustissimaen
dcterms.abstractAcacia angustissima has potential in agroforestry systems for forage production in tropical environments. However, feeding trials indicate that the leaves are potentially toxic. Signs of toxicity in sheep are similar to those presented by sheep fed flatpea (Lathyrus sylvestris) hay which contains a high concentration of the non-protein amino acid 2,4-diaminobutanoic acid (DABA). Cation exchange chromatography, high-performance liquid chromatography (HPLC) and NMR were used to isolate and identify the non-protein amino acid in A angustissima leaves. A quantitative HPLC method was used to determine the content of the non-protein amino acid in leaves from 20 accessions. The non-protein amino acid was identified as 4-N-acetyl-2,4-diaminobutanoic acid (ADAB), previously reported to occur in seeds. The average and range in ADAB content were 16.8 and 10.6-25.4mgg -1 respectively. This content of ADAB is higher than the levels of DABA in flatpea hay that are toxic to sheep.en
dcterms.accessRightsLimited Access
dcterms.available2001
dcterms.bibliographicCitationJournal of the Science of Food and Agriculture;81(15): 1481-1486en
dcterms.extentp. 1481-1486en
dcterms.issued2001-12
dcterms.languageen
dcterms.licenseCopyrighted; all rights reserved
dcterms.publisherWileyen
dcterms.subjectacacia angustissimaen
dcterms.subjectamino acidsen
dcterms.subjectleavesen
dcterms.subjecthplcen
dcterms.subjectpoisoningen
dcterms.subjectcationsen
dcterms.subjectionsen
dcterms.subjectnmr spectroscopyen
dcterms.subjectchemical compositionen
dcterms.subjectanalytical methodsen
dcterms.typeJournal Article

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