Quantifying the transmission of antimicrobial resistance at the human and livestock interface with genomics

Simple item page
cg.authorship.typesCGIAR and advanced research instituteen_US
cg.contributor.affiliationUniversity of Edinburghen_US
cg.contributor.affiliationInternational Livestock Research Instituteen_US
cg.contributor.crpAgriculture for Nutrition and Healthen_US
cg.contributor.donorJoint Programming Initiative on Antimicrobial Resistanceen_US
cg.contributor.donorDarwin Trust of Edinburghen_US
cg.contributor.donorBiotechnology and Biological Sciences Research Council, United Kingdomen_US
cg.contributor.donorEconomic and Social Research Council, United Kingdomen_US
cg.contributor.donorNatural Environment Research Council, United Kingdomen_US
cg.contributor.donorNovo Nordisk Foundationen_US
cg.creator.identifierDishon Muloi: 0000-0002-6236-2280en_US
cg.howPublishedFormally Publisheden_US
cg.identifier.doihttps://doi.org/10.1016/j.cmi.2020.09.019en_US
cg.isijournalISI Journalen_US
cg.issn1198-743Xen_US
cg.issue12en_US
cg.journalClinical Microbiology and Infectionen_US
cg.reviewStatusPeer Reviewen_US
cg.subject.ilriAGRI-HEALTHen_US
cg.subject.ilriAMRen_US
cg.subject.ilriGENETICSen_US
cg.subject.ilriHUMAN HEALTHen_US
cg.subject.ilriLIVESTOCKen_US
cg.volume26en_US
dc.contributor.authorWee, B.A.en_US
dc.contributor.authorMuloi, D.M.en_US
dc.contributor.authorBunnik, B.A.D. vanen_US
dc.date.accessioned2020-11-12T13:53:39Zen_US
dc.date.available2020-11-12T13:53:39Zen_US
dc.identifier.urihttps://hdl.handle.net/10568/110142en_US
dc.titleQuantifying the transmission of antimicrobial resistance at the human and livestock interface with genomicsen_US
dcterms.abstractBackground Livestock have been implicated as a reservoir for antimicrobial resistance (AMR) that can spread to humans. Close proximity and ecological interfaces involving livestock have been posited as risk factors for the transmission of AMR. In spite of this, there are sparse data and limited agreement on the transmission dynamics that occur. Objectives To identify how genome sequencing approaches can be used to quantify the dynamics of AMR transmission at the human–livestock interface, and where current knowledge can be improved to better understand the impact of transmission on the spread of AMR. Sources Key articles investigating various aspects of AMR transmission at the human–livestock interface are discussed, with a focus on Escherichia coli. Content We recapitulate the current understanding of the transmission of AMR between humans and livestock based on current genomic and epidemiological approaches. We discuss how the use of well-designed, high-resolution genome sequencing studies can improve our understanding of the human–livestock interface. Implications A better understanding of the human–livestock interface will aid in the development of evidence-based and effective One Health interventions that can ultimately reduce the burden of AMR in humans.en_US
dcterms.accessRightsOpen Accessen_US
dcterms.audienceScientistsen_US
dcterms.bibliographicCitationWee, B.A., Muloi, D.M. and Bunnik, B.A.D. van. 2020. Quantifying the transmission of antimicrobial resistance at the human and livestock interface with genomics. Clinical Microbiology and Infection 26(12): 1612–1616.en_US
dcterms.extentp. 1612-1616en_US
dcterms.issued2020-12en_US
dcterms.languageenen_US
dcterms.licenseCC-BY-4.0en_US
dcterms.publisherElsevieren_US
dcterms.subjectantimicrobial resistanceen_US
dcterms.subjectlivestocken_US
dcterms.subjecthealthen_US
dcterms.subjecthumansen_US
dcterms.subjectgenomicsen_US
dcterms.typeJournal Articleen_US

Files

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ILRI articles in journals
CGIAR Antimicrobial Resistance Hub documents
CRP A4NH outputs
Epidemiology, ecology and socio-economics of disease emergence in Nairobi (Urban Zoo)
ILRI A4NH improving human health flagship outputs ( (2012-2021)