Genetic characterization of infectious bursal disease virus isolates in Ethiopia

cg.contributor.crpLivestock and Fish
cg.contributor.donorBiotechnology and Biological Sciences Research Council, United Kingdomen
cg.contributor.donorDepartment for International Development, United Kingdomen
cg.contributor.donorScottish Governmenten
cg.coverage.countryEthiopia
cg.coverage.iso3166-alpha2ET
cg.coverage.regionAfrica
cg.coverage.regionEastern Africa
cg.howPublishedFormally Publisheden
cg.identifier.doihttps://doi.org/10.1016/j.actatropica.2013.09.025en
cg.isijournalISI Journalen
cg.issn0001-706Xen
cg.journalActa Tropicaen
cg.reviewStatusPeer Reviewen
cg.subject.ilriANIMAL DISEASESen
cg.subject.ilriGENETICSen
cg.subject.ilriINDIGENOUS BREEDSen
cg.subject.ilriLIVESTOCKen
cg.subject.ilriPOULTRYen
cg.subject.ilriCHICKENSen
cg.volume130en
dc.contributor.authorJenberie, S.en
dc.contributor.authorLynch, Stacey E.en
dc.contributor.authorKebede, F.en
dc.contributor.authorChristley, Robert M.en
dc.contributor.authorGelaye, E.en
dc.contributor.authorNegussie, H.en
dc.contributor.authorAsmare, K.en
dc.contributor.authorAyelet, G.en
dc.date.accessioned2013-11-03T13:35:22Zen
dc.date.available2013-11-03T13:35:22Zen
dc.identifier.urihttps://hdl.handle.net/10568/33888
dc.titleGenetic characterization of infectious bursal disease virus isolates in Ethiopiaen
dcterms.abstractThe objective of the investigation was to characterize infectious bursal disease viruses (IBDV) circulating in commercial and breeding poultry farms in Ethiopia between 2009 and 2011. The nucleotide and deduced amino acid sequence for VP2 hypervariable region of ten IBDVs were determined by RT-PCR, sequenced and compared to well characterised IBDV isolates worldwide. IBDV genetic material was amplified directly from bursa or cell passaged material. Phylogenetically, Ethiopian IBDVs represented two genetic lineages: very virulent (vv) IBDVs or variants of the classical attenuated vaccine strain (D78). The nucleotide identity between Ethiopian vvIBDVs ranged between 0% to 2.6%. Ethiopian vvIBDVs are clustered phylogenetically with the African IBDV genetic lineage, independent of the Asian/European lineage. This report demonstrates the circulation of vvIBDV in commercial and breeding poultry farms in Ethiopia.en
dcterms.accessRightsOpen Access
dcterms.audienceScientistsen
dcterms.bibliographicCitationJenberie, S., Lynch, S.E., Kebede, F., Christley, R., Gelaye, E., Negussie, H., Asmare, K. and Ayelet, G. 2013. Genetic characterization of infectious bursal disease virus isolates in Ethiopia. Acta Tropica 130: 39-43.en
dcterms.extentp. 39-43en
dcterms.issued2014-02en
dcterms.languageen
dcterms.licenseCC-BY-3.0
dcterms.publisherElsevieren
dcterms.subjectanimal diseasesen
dcterms.subjectgeneticsen
dcterms.typeJournal Article

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